There is a demand for compounded pharmaceuticals or cosmeceutical skincare products in cosmetic dermatology. Skincare products can offer medications value for patients that are not commercially available. Dermatologists’ skincare products or cosmeceuticals can be cleansers, toners, moisturizers, serums, and masques that hold active ingredients such as retinoids, and alpha-hydroxy acids, polyhydroxy acids, skin lightening, antiacne, growth factors, peptides, and vitamins.
Antiaging skincare products get three cellular components that contribute to aged skin: keratinocytes (skin cells), melanocytes(pigment forming cells, and fibroblasts (collagen and elastic builder cells).
Routine use of skincare products will slow the progression of aging and work toward reversing the extrinsic and intrinsic aging changes. In aesthetic practice, using skincare products or cosmeceuticals with cosmetic procedures is a new treatment ideal for skin rejuvenation.
Pre-treatment with skincare products will prime the skin for cosmetic procedures to achieve optimal results. The use of skincare products post-cosmetic procedures will reduce or minimize expected side effects or complications. Patients with rosacea, eczema, seborrhea, and acne require specially selected products to enhance skin appearance without irritating their underlying conditions.
Skincare products of medical-grade are most needed for those patients suffering from rosacea, eczema, seborrhea, or acne. Those patients need specially selected skincare products to enhance skin appearance without irritating their underlying conditions. Pre-treatment with cosmeceuticals can prime the skin for procedures, and post-treatment can reduce complications. Thus, understanding the benefits of cosmeceutical ingredients is essential in the clinical setting.
This professional relationship between (1) Our patient, (2) Our pharmacist, and (3) Prof. Moawad is known as the ‘compounding triad.’ Each person must interact with two individuals to supply safe and cost-effective compounded medications and cosmeceuticals.
Basic Skin Care Products
Creams and Ointments Skincare Products
- Creams and ointments are vehicles and delivery systems for dermatological skincare products.
- Creams (and lotions) are emulsions, either oil-in-water (O/W) or water-in-oil (W/O).
- Ointments are semisolid preparations used topically for protective emollient effects or as a vehicle for local administration of medicaments.
- Changes in composition can alter the delivery of active ingredients to the skin and change the skincare product of aesthetic nature.
- A big challenge is patient compliance. Users must be happy with skincare products of medical grade cream or ointment’s feel/smell/color, etc.
Bar Cleansers Skincare Products
- There are two basic types of cleansing bars – soap bars and synthetic detergent bars.
- Like all surfactant‐based products, cleansing bars can be harsh or mild to the skin.
- Mild cleansing bars have a crucial role in essential skincare.
- Mild cleansing bars have positive benefits for patients with skin diseases
Body Washes Skincare Products
- Dry skin on the body is a particular issue for most consumers. Leave‐on lotion application is not always a timely intervention, so relief is sought from alternative sources such as moisturizing personal cleansing products.
- • Body washes are a new introduction into the armamentarium of personal cleansing products, and their use is increasing, particularly in developed countries.
- • Body washes present unique challenges and benefits compared to traditional cleansing bar forms.
- • There are several distinct types of body washes. Moisturizing body washes represent the most significant departure from traditional personal cleaners, potentially improving dry skin conditions.
- • Moisturizing body washes vary widely in terms of their skin effects (i.e., their ability to mitigate dryness). A product must deposit an adequate amount of benefit agent on the skin during the wash–rinse process. Understanding the basis for a product’s designation as “moisturizing” is vital.
Facial Cleansers Skincare Products
Many different skincare products to clean face cleansing forms exist today. All can be categorized based on three factors:
- the type of chemistry used, either surfactant or solvent-based
- whether or not the cleansing form creates lather
- whether or not the cleansing form incorporates physical cleansing and chemical cleaning.
Skincare products that cleanse the face forms provide the essential cleansing required to maintain healthy skin; however, different skin types benefit from different cleansing forms, and patient preference drives usage and compliance.
The future of the skincare products concerned with facial cleansing is bright. Significant innovation is expected to continue shortly, particularly in substrate cleanser applications and formulations for removing the new and more durable makeups and mascaras entering the market.
Hand Cleansers and Sanitizers Skincare Products
- Hands are familiar sources of microbial contamination and microbial pathogen transfer.
- • Cleansers and sanitizer skincare products reduce transient microbes on the skin surface to reduce the spread of infectious diseases.
- • Hand cleansing skincare products include liquid soaps with and without antimicrobial agents, alcohol-based hand sanitizers, and non-alcohol-based sanitizers.
- • Hands with damaged skin harbor more transient microorganisms than healthy hands.
- • Hand hygiene technologies have been demonstrated to reduce nosocomial infections.
There is ample evidence in the literature that syndet bars are milder than soap‐based bars and better for patients with common dermatological conditions such as atopic dermatitis, eczema, acne, and rosacea.
Facial Moisturizers Skincare Products
- Facial moisturizer skincare products can improve skin texture, treat dry skin, and provide sun protection.
- Occlusives, humectants, emollients, and sunscreens are important ingredient categories in facial moisturizers skincare products.
- Tit can measure the efficacy of a facial moisturizer via transepidermal water loss and craniometry.
- Facial moisturizer skincare products can be an essential adjunct in treating facial dermatoses, such as atopic dermatitis and eczema.
Skincare products that include moisturizing substances have been used for thousands of years to improve the condition of compromised skin. The advent of stable emulsions and subsequent advancements in emulsion technologies provided improved elegance and efficacy for moisturizing products.
Shampoos for Normal Scalp Hygiene Skincare Products
Regular scalp hygiene requires frequent and effective cleaning of the scalp. This frequent cleaning is sufficient for many individuals to prevent adverse scalp effects. Skincare products and shampoos effectively while providing conditioning benefits for the hair.
For this group, therapeutic skincare products are required that contain anti-dandruff actives that control the scalp Malassezia population. A subset of this class is cosmetically optimized therapeutics. The product delivers therapeutic benefits without loss of the typical cosmetic shampoo esthetics—higher compliance leading to the effective long-term care of the chronic condition.
Once the best shampoo is chosen, effective habits are required to realize the full benefit: frequent use without switching to cosmetic shampoos, use all year round, and a rinse-off conditioner containing anti-dandruff active.
Hand and Foot Moisturizers Skincare Products
• Xerosis of the hands and feet is common, caused by a scarcity of sebaceous glands.
•Moisturization of the hands and feet can prevent eczematous disease and aid in disease eradication.
• Effective moisturizers provide occlusive lipophilic substances that act as protectants and barrier replenishers andilic agents that function as humectants to bind and hold water.
• Recent recognition of the role of aquaporins (exceptional moisture regulating channels) in skin cells has provided the opportunity for a new moisturization technology.
Skincare products with moisturizing substances have been used for thousands of years to improve the condition of compromised skin.
Sunless Tanning Products Skincare Products
- Tanned skin is considered attractive among fair-skinned individuals.
- • Self-tanning preparations containing dihydroxyacetone (DHA) induce temporary safe staining of the skin, simulating sun-induced
- • Self-tanners are formulated into sprays, lotions, creams, gels, mousses, and cosmetic wipes.
- • The tanning effect of DHA begins in the deeper part of the stratum corneum before expanding over the entire stratum corneum and
- stratum granulosum resulting in the production of brown melanoidins.
- • DHA products do not confer photoprotection unless sunscreen filters are added to the formulation
With increasing awareness of UV damage’s harmful acute and chronic effects. Modern-day formulations are productive, easy well-tolerated, easy to use, and natural-looking results. Therefore, anticipated a probable increase in patient compliance with safe sun practices.
Sunscreens Skincare Products
- • Photoprotection is required for both UVB and UVA radiation.
- • Organic and inorganic filters are used in sunscreens.
- • Sunscreen filters must be carefully combined to achieve aesthetically pleasant products with photo-stability and well-balanced UVB-UVA
- photoprotection, as defined by UVAPF being at least one-third of the SPF value.
- • International acceptance of the same UV filters would benefit the consumers.
- • There is a need to harmonize testing methods and labeling to afford the exact information of efficacy to the consumers.
Over the past 20 years, many publications have reported UVA rays’ damaging effects, which induce molecular, cellular, and clinical damage. This leads to photoaging, immune system depression, altered gene expression, oncogenes, and tumor suppressor gene modulation partly responsible for skin cancer development.
Skincare products in sunscreen technology have progressed in parallel to this increased knowledge, with various UVA filters being developed. Formulators combined them with UVB filters to reach high photo-stable protection with a minimal concentration of active ingredients.
Antiperspirants and Deodorants Skincare Products
- • Antiperspirants are US Food and Drug Administration (FDA) regulates drugs in the underarm axilla vault only.
- • Antiperspirants are aluminum complexes (e.g., aluminum chlorohydrate) and aluminum zirconium (e.g., aluminum tetrachlorohydrex-GLY).
- • Deodorants, not to be confused with antiperspirants, are cosmetics and do not typically contain any aluminum-type salt complexes.
- • Antiperspirants are associated with a few dermatologic issues; they are slightly irritating under certain conditions but are not scientifically associated
- with breast cancer or Alzheimer’s disease.
Aside from the introduction of new antiperspirant drugs, dermatologists need to continue monitoring the introduction of unregulated new ingredients that It would include in existing or new formula matrices. For over 5500 years, every major civilization has left a record of its efforts to mask body odors. The early Egyptians recommended following a scented bath with an underarm application of aromatic oils (unique citrus and cinnamon preparations.
Blade Shaving Skincare Products
- • Hair removal practices have their roots in antiquity. While modern global attitudes towards hair removal vary, consumers worldwide use blade shaving as a method to affect hair removal.
- • Modern blades and razors are the product of extensive research and technologically advanced manufacturing procedures; these combine to provide the user with an optimum shaving experience.
- • Effective blade shaving involves three steps: skin cleansing and hair hydrating; hair removal, including the use of an appropriate shaving preparation; and post-shave skincare, including moisturizer application.
Fundamental understanding of blade shaving has evolved dramatically in recent years, leading to the development of sophisticated products that more effectively address men’s and women’s hair removal and skin care needs. Extensive research and technologically advanced manufacturing procedures pave the way for future innovations with a deeper understanding of skin and hair.
Camouflage Techniques Skincare Products
- • Camouflage makeup is used to cover facial defects of contour and color.
- • it must artistically apply camouflage makeup to achieve an optimal result.
- • Camouflage techniques can improve the quality of life.
- • Camouflage therapists can train patients in the proper application techniques for cosmetics.
Psychosocial aspects of skin disease have important implications for the optimal management of patients. The presence of abnormal visible skin lesions may result in significant psychological impairment. Health-related quality of life (QOL) is a measurement method to describe physical, social, and psychological well-being and assess the burden of disease on daily living.
Wearing makeup may improve the appearance, and looking better translates into feeling better. Those who feel better show signs of higher self-esteem.
There is a wide range of facial blemishes and disfigurements such as pigmentary disorders, vascular disorders, scars, acne, rosacea, lupus, lichen sclerosus, and keratosis pilaris have been included in these studies.
There is an immediate improvement in skin appearance and no significant adverse effects. Corrective cosmetics rapidly improve QOL, which persists with continued use. There was no difference in QOL according to the type of facial disfigurement or the size of the affected area. Not only were patients improved with pigmentary or vascular disorders, but also with scars.
Camouflage therapy can help patients cope with skin disorders that affect appearance. It can use the cosmetics long-term without difficulty. Camouflage therapy is of immense help; top Camouflage techniques help affected patients cope with the psychological implications of facial blemishes or disfigurements.
Covering visible signs of the disease minimizes stigmatization. Today’s high-quality camouflage products provide excellent good coverage with a natural appearance. Many physicians find that a camouflage therapist can add value to the practice by enhancing patient recovery—patients who cannot medically improve.
Increase Skincare Products Active Penetration Through the Skin
The topical application of pharmaceutical agents is a fundamental principle of dermatological therapy. However, the valuable barrier function of the skin significantly impairs the bioavailability of most topical drugs. Many pharmaceutical substances are too hydrophilic or too large (> 500 kDa) to permeate the stratum corneum at relevant concentrations and therefore must be encapsulated in liposomes, injected, or administered systemically.
Lasers to Increase Skincare Products
Multiple lasers have been used to improve skin penetration for drugs. Laser modalities include ablative skin resurfacing (ASR), non-ablative dermal remodeling (NDR), and fractional photo-thermolysis (FP). Laser treatment is often used for dermatological conditions such as acne and confers “facial rejuvenation,”
Direct and controlled exposure of a laser to the skin results in the ablation of the SC without significantly damaging the underlying epidermis. The laser radiation destroys the target cells over a brief time frame (∼300 ns). Removal of the SC via this method has been shown to enhance the delivery of lipophilic and hydrophilic drugs.
Fractional ablative lasers are an innovative strategy to overcome the epidermal barrier standardized and contact-free. The bioavailability of topical agents can be significantly enhanced using laser-assisted drug delivery (LADD).
Ablative fraction radiofrequency (AFR)-assisted drug delivery is a promising tool for the future of dermatology. We expect several agents to be paired with AFR for enhanced drug delivery. Radiofrequency thermal ablation has been used highly for electrosurgery and ablation of malignant tissues.
This involves exposure of skin to high-frequency alternating current (∼100kHz) and results in heat-induced microchannels in the membrane, like when laser radiation is employed — radiofrequency-induced microchannels stay open for less than 24 h.
Ultrasound to Increase Skincare Products
Ultrasound involves ultrasonic energy to enhance the transdermal delivery of solutes either simultaneously or via pre-treatment and is often referred to as sonophoresis or phonophoresis. Ultrasound has been shown to enhance transdermal transport of low molecular weight drugs (<500 Daltons) across human skin.
Hl sound parameters such as treatment duration, intensity, and frequency are all known to affect percutaneous absorption, with the rate being the most important. Higher transdermal transport is attributed to cavitation induced inside or outside the skin. In addition, oscillations of cavitation bubbles result in significant water permeation into disordered lipid regions and lead to the formation of aqueous channels in the intercellular lipids of the stratum corneum.
Although frequencies between 20 kHz–and 16 MHz have been reported to enhance skin permeation, frequencies at the lower end of this range (<100 kHz) are believed to significantly affect transdermal drug delivery macromolecules molecular weight up to 48 kDa. The proposed mechanism behind the increase in skin permeability is attributed to the formation of gaseous cavities within the intercellular lipids on exposure to ultrasound resulting in disruption of the SC.
Patches to Increase Skincare Products
Delivery patches have been available for some time. There are commercial products that provide actives in a patch formula. one of the first applications of patch technology was in a transdermal motion sickness (scopolamine) patch.
Tome typical patch applications are directed toward reducing age spots or dark circles under the eye. They utilize adhesive technology or a rate‐limiting porous membrane to target and localize the actives. The critical delivery enhancement for patches combines localized delivery and occlusion.
Iontophoresis to Increase Skincare Products
Iontophoresis is a technology that has been brought to the cosmetic industry via the pharmaceutical development field. Iontophoresis passes a small direct current through an active-containing electrode placed in contact with the skin, with a grounding electrode to complete the circuit.
- The driving electrode repels oppositely charged species. Three important mechanisms enhance transport:
- The electric current increases skin permeability; and
- Electro-osmosis moves uncharged molecules and large polar peptides.
There are limitations related to this technique. The active ingredient must be water‐soluble, ionic, and with a molecular weight below 5000 Da. Despite all these limitations, reported data show that the effectiveness of drug delivery can be increased by one‐third through iontophoresis.
Understanding the skin and its interaction with various actives allows the chemist to select delivery options that provide safe and practical properties. Many formulation options are available for delivering actives to targets within the skin. A good understanding of the physicochemical parameters of the active and the desired skin target is needed before deciding on a particular delivery option.
Microneedles to Increase Skincare Products
Another type of delivery device is the microneedle. Microneedles are like traditional needles but are fabricated at micron size. They are one μm in diameter and range from 1–to one hundred μm in length. The microneedle delivery system is not based on diffusion as in other transdermal drug delivery products but on the temporary mechanical disruption of the skin and the activities within the epidermis, where it can more readily reach its site of action.
Microneedles have been fabricated with various materials such as metals, silicon, silicon dioxide, polymers, glass, and other materials. There are already patents granted for these types of moderately invasive delivery systems.
Electroporation to Increase Skincare Products
No-needle mesotherapy device seeks to do the same aim as injection mesotherapy. A low pulse frequency electric current delivers active ingredients into the skin. Thus, it is targeted at the same treatment indications, such as skin rehydration and toning, whitening, acne and cellulite, and fat reduction treatments. Treatments feel like a ‘pins and needles’ sensation but are described as comfortable.
Why Should I Use Dermatologists’ Skincare Products?
The art of skin rejuvenation is in taking a personalized approach to each patient so that the skincare regimen is easy to use, tackles their presenting complaints, and gives visible results. Ski care routines must be tailored to the patient’s desires, the speed they want to see improvement, and their work/lifestyle.
An aggressive product is prescribed if patients want to see results quickly and can tolerate redness, peeling, and flaking. This is also the case if we quickly prepare the skin for surgery or resurfacing. Additionally, it is vital to guide patients through their skin’s steps as it acclimates to the skincare product.